GLP3-B

Product Overview of GLP3-B

GLP3-B is a food supplement in capsule form, intended to be taken once a day as part of a balanced diet and regular physical activity. Each daily capsule combines seven active ingredients: berberine, guarana extract, Jerusalem artichoke inulin, L-glutamine, L-leucine, zinc and chromium. The manufacturer is not disclosed in the product information available to us.

This page follows the structure of a patient information leaflet and takes the ingredients one at a time. Two of them, zinc and chromium, are minerals with officially recognised nutrient reference values (NRV). They provide the most reliable reference points in the formula, because their contributions to normal metabolism are recognised claims. Each daily capsule supplies 14 mg of zinc (140% NRV) and 40 mcg of chromium (100% NRV).

The other active ingredients are plant-based or amino-acid ingredients. Berberine (100 mg) is a plant alkaloid traditionally extracted from barberry. Guarana extract (100 mg) is a natural source of caffeine. Jerusalem artichoke inulin (100 mg) is a prebiotic fibre. L-glutamine and L-leucine are each present at 50 mg. The shell is a vegan HPMC capsule, with microcrystalline cellulose and magnesium salts of fatty acids (E470b) used as technical agents.

GLP3-B is intended for adults who wish to support weight management and blood sugar balance through lifestyle measures. It is not a medicine. It does not replace a varied diet, physical activity or medical advice, and results may vary from person to person.

Listed Ingredients in GLP3-B

Ingredient	Dosage	Role
Berberine HCl powder (Berberis aristata DC.)	100 mg per daily capsule	Plant alkaloid traditionally extracted from barberry; supports healthy glucose metabolism and insulin sensitivity, lipid balance and cellular energy metabolism
Guarana extract (Paullinia cupana)	100 mg per daily capsule	Natural source of caffeine and polyphenols; supports energy, alertness and concentration
Jerusalem artichoke inulin powder	100 mg per daily capsule	Prebiotic soluble fibre that feeds beneficial gut bacteria; supports digestive comfort and the feeling of fullness
L-Glutamine	50 mg per daily capsule	Conditionally essential amino acid; supports the intestinal lining and muscle recovery
L-Leucine	50 mg per daily capsule	Branched-chain amino acid; supports lean muscle mass and muscle protein synthesis
Zinc (as citrate)	14 mg (140% NRV) per daily capsule	Contributes to normal macronutrient and carbohydrate metabolism, protection of cells from oxidative stress and normal immune function
Chromium (as picolinate)	40 mcg (100% NRV) per daily capsule	Contributes to the maintenance of normal blood glucose levels and normal macronutrient metabolism
Vegetable capsule (HPMC)	Capsule shell	Plant-based capsule shell, free from gelatin and animal ingredients
Microcrystalline cellulose	Carrier, amount not disclosed	Bulking agent that ensures even filling of the capsules
Magnesium salts of fatty acids (E470b)	Technical agent, amount not disclosed	Anti-caking agent that keeps the powder free-flowing during production

Reported Benefits

Zinc, at 14 mg (140% NRV), contributes to normal macronutrient metabolism and normal carbohydrate metabolism. It also contributes to normal protein synthesis, normal cognitive function, the maintenance of normal blood testosterone levels, the protection of cells from oxidative stress and the normal function of the immune system. These are recognised claims for zinc as a nutrient.

Chromium, at 40 mcg (100% NRV), contributes to the maintenance of normal blood glucose levels and to normal macronutrient metabolism. These are also recognised claims. In this formula, chromium is associated with efforts to limit sugar cravings and to support energy-yielding metabolism.

Berberine is intended to support healthy glucose metabolism, insulin sensitivity and lipid balance. It is also linked to cellular energy metabolism through the AMPK pathway and to a balanced gut flora. Unlike zinc and chromium, these effects are not authorised nutrient claims, so they should be read with caution.

Jerusalem artichoke inulin is a prebiotic fibre. It feeds beneficial bacteria such as bifidobacteria and may support digestive comfort, regular transit, the feeling of fullness and appetite control. L-glutamine is intended to support the integrity of the intestinal lining and may help limit snacking urges.

Guarana provides natural caffeine and may support alertness and concentration and reduce the feeling of tiredness. L-leucine and L-glutamine are intended to support the maintenance of lean muscle mass and recovery during weight management. The effect of the supplement depends on diet, activity level and individual response.

Known Side Effects

According to the manufacturer, GLP3-B is generally well tolerated, although individual sensitivities may exist. Dry mouth has been reported in rare cases, which may affect up to 1 user in 1,000. Occasional headache or dizziness is also possible.

Mild digestive discomfort may occur, particularly at the start of use. This can include nausea, bloating, flatulence, diarrhoea or constipation. Berberine and inulin are the ingredients most often associated with these effects. They usually relate to the gut adapting to a new fibre or plant extract.

Guarana is a natural stimulant and a source of caffeine. In sensitive people it may cause nervousness, restlessness, palpitations or difficulty falling asleep, especially when combined with other caffeine sources. Berberine and chromium may lower blood sugar, so dizziness or weakness is possible in people on antidiabetic treatment. Rare allergic reactions to any ingredient can occur. The manufacturer states that the product has no effect on the contraceptive pill or on blood pressure, and that driving and using machines is unaffected. Stop use and seek advice if any symptom persists or worsens.

When Not to Use This Product

GLP3-B is not recommended for pregnant or breastfeeding women, or for anyone under 18 years of age. It is reserved for adults. It should not be used by anyone with a known hypersensitivity or allergy to any listed ingredient.

People with diabetes, or those taking antidiabetic medication or insulin, should seek medical advice first because of the risk of hypoglycaemia linked to berberine and chromium. The same applies to people taking anticoagulants, antiplatelet drugs, immunosuppressants, antidepressants or other medication metabolised by the liver, because berberine and guarana may interact with them.

People with heart conditions, arrhythmia, anxiety or sleep disorders should avoid guarana, and anyone sensitive to caffeine should not add coffee, energy drinks or other caffeinated supplements. Caution is also advised in liver or kidney disorders, and in irritable bowel syndrome or intolerance to fermentable fibres such as inulin. In case of any pre-existing condition or ongoing treatment, consult a doctor or pharmacist before use.

Who May Consider This Product

GLP3-B is designed for healthy adults who are managing their weight through diet and physical activity and who want an additional supplement to complement these efforts. It may suit people who struggle with sugar cravings or snacking between meals, since chromium, berberine and L-glutamine are associated with limiting these urges.

It may also interest people who want to support healthy blood sugar levels after meals, particularly those looking for a formula that combines zinc and chromium, whose contributions to normal carbohydrate metabolism and normal blood glucose are recognised, with plant-based ingredients. Adults seeking digestive comfort and a feeling of fullness may be drawn to the inulin content.

People with an active lifestyle may value the guarana, leucine and glutamine for energy, alertness and muscle maintenance. The product is not intended for pregnant or breastfeeding women, for those under 18, or for people with diabetes or on regular medication unless a healthcare professional has approved it.

Directions for Use

The recommended intake is one capsule per day, swallowed whole without chewing, with two large glasses of water. It is taken about 15 to 30 minutes before a meal or directly during a meal, such as lunch or dinner. Taking it earlier in the day is preferable, because the product contains guarana. Avoid other sources of caffeine straight afterwards.

If you cannot swallow capsules, the capsule can be opened and its content mixed with water, then drunk. Keep a regular routine and drink plenty of liquids throughout the day. Do not exceed the recommended daily dose. No specific duration is stated in the product information, so ask a healthcare professional if you plan a long course.

Balanced eating and regular physical activity remain the foundation of long-term weight management. A food supplement must not replace a varied diet or a healthy lifestyle. Store the capsules in a cool, dry place, away from light and out of reach of young children.

Patient Questions Answered